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Histological changes about CYP-induced hemorrhagic cystitis were reduced in treated animals: infiltration of the cells, oedema, and hemorrhage indicated the preventive effect of TQ (Gore et al., 2016)

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Supplementary Data 13 Plasmid map of pET16_10His_PykF(L303H)

Mitochondrial isolation was performed using the Mitochondria Isolation Kit for Cultured Cells based on the manufacturers manuals (Thermo Fisher Scientific)

The anabolic variety and redox status of GSH in the myocardium under pathological conditions When the heart is under stress from pathological factors, GSH redox homeostasis is disrupted, which is manifested by a significant decrease in GSH content and accumulation of GSSG in the myocardium